Clivus chordoma pdf files

Case report a 77 yearold female presented with a oneyear long history of progressively worsening headaches, alongwith a 3. Skull base approaches to clival chordomas request pdf. Chordomas are rare tumours of the bone arising along the spine from clivus to sacrum. Under the impression of acoustic schwannoma, the patient underwent operation.

The pathologic diagnosis was chordoma in 3 patients, osteosarcoma in 2, chondrosarcoma in 2, malignant schwannoma in 1, and ewings sarcoma in 1. Introduction to mechatronic design carryer pdf extraosseous spinal chordoma in. For more inferior lesions, we have modified the transoraltranspharyngeal approach by. After a oneyear cultivation period, the mugcc1 cell line was established and the chordoma cells were characterized phenotypically. Pdf chordomas are rare tumors that can develop anywhere along the craniospinal axis. Once files have been uploaded to our system, change the order of your pdf documents. All cases with limitation of abduction from 2to 3 were. Rearrange individual pages or entire files in the desired order. We compared three chordoma cell lines of the clivus region including the.

Giant clival chordoma causing pathological laughter. Endoscopic endonasal transclival resection of chordomas. Once you merge pdfs, you can send them directly to your email or download the file to our computer and view. New developments in radiation therapy have improved recurrencefree survival in patients with chordomas. Intradural extraosseous chordoma has clearly different features from those of typical chordoma it is uncommon, occurs almost exclusively in the prepontine and clival regions, and is encountered in 0. Characterization of clivus chordoma tumor cell line mugcc1. Hoxa7, hoxa9, and hoxa10 are differentially expressed in. On initial evaluation, the patient had ataxic gait. Transcranial approaches to clival chordomas provide a circuitous route to the site of origin of the tumor often involving extensive bone drilling and. After removal of a clival chordoma extending from the sellar region to the.

Metastatic disease to the clivus mimicking clival chordomas. Get a printable copy pdf file of the complete article 1. Chordoma, a rare bone tumor that occurs along the spine, has led scientists on a fascinating. All authors read and approved the final manuscript. Dpt case presentation schedule 2019 university of iowa. The clival chordoma and chondrosarcoma are the most common of these tumors.

Best practices for the management of localregional recurrent. Ks was the major contributor in writing the manuscript. In this paper, we describe a case of clival chordoma, discuss various diagnostic modalities available to differentiate chordomas from other tumors, and describe therapeutic options including adjuvants. Chordomas are rare, malignant bone tumors of the skullbase and axial skeleton. Establishment of clival chordoma cell line mugcc1 and. Chordoma is a rare neoplasm considered to be of low to intermediate malignancy and originating from the notochord cells. Pilar merino, md, phd, gema franco, md, and rosario gomez. Expert recommendations for the diagnosis and treatment of. The sphenoid sinus and upper clivus are then exposed for tumor removal. The authors describe a case of a giant clivus chordoma in a 42yearold male presenting with symptoms due to compression of the brain stem and hypothalamus, including the unusual manifestation of pathological laughter. Chordoma chondrosarcoma clivus abducens nerve proton beam therapy brachyury.